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900 MHz probe development for MRI of live mice

General

Magnetic resonance imaging is another important capability of the 900's wide bore. 900 MHz RF transmitter/receiver coils and animal handling equipment are being developed at NHMFL by Nate Falconer and Victor Schepkin to support the magnetic resonance imaging user program. The resulting imaging coils and animal support systems will enable the 900 UWB to be used for in-vivo brain studies in animals as large as adult rats.



An animal probe with interchangeable RF imaging coils.

1H and 23Na coils for the live mouse brain are being field-tested. This project is a collaborative effort with the MRI program at the AMRIS facility at the University of Florida.

click to see all slices

Test 1H images of the live mouse brain.  Left: 62x62 micron resolution in 150 micron slice [see all slices].  Right: 70x70 micron resolution in 200 micron slice.